What is Tudca? | Information & Faq
Amyotrophic Lateral Sclerosis (ALS) is a rapidly progressive neurological disease which attacks the neurons involved with voluntary movement, called motor neurons. It is also known as Motor Neuron Disorder (MND) or Lou Gherig’s Disease. ALS is a disease which doesn’t have a wide range of treatment options, although there have been advances and a lot of research is ongoing.
What is ALS?
ALS is a progressive neurodegenerative disease which leads to severe disability, and eventually results in death. The disability, which is caused by the loss of voluntary function, is directly connected to the damage and gradual loss of motor neurons. Motor neurons are nerve cells that extend from the brain down to the spinal cord and to muscles throughout the body. They are essential for sending messages from the brain to the muscles.
For more details see the references at the bottom of the page.
How does ALS affect the body?
For more details see the references at the bottom of the page.
Who gets ALS?
For more details see the references at the bottom of the page.
Is there a cure for ALS?
Unfortunately, there is currently no cure for ALS. However, as stated by medical centre the Mayo Clinic:
"Treatments can't reverse the damage of amyotrophic lateral sclerosis, but they can slow the progression of symptoms, prevent complications and make you more comfortable and independent.".
Treatments are designed to relieve symptoms and improve the quality of life for individuals. Supportive care is best provided by multidisciplinary teams of healthcare professionals such as doctors, nurses, and a variety of therapists, with the aim of keeping patients as mobile and comfortable as possible 2.
Medicines for treating ALS
These are some of the medicines that are used to treat patients with ALS. This is not intended to be a comprehensive list or guide.
Edaravone (Radicut/Radicava)
A radical scavenger approved by the Japanese PMDA and in the American FDA for the treatment of ALS.
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Edaravone generic
A generic ✢ version of edaravone, produced by several manufacturers. It is approved by the Japanese PMDA for the treatment of cerebral infarction.
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Ibudilast (Ketas)
It has an anti-inflammatory and neuroprotective effect on the brain. It has been granted orphan drug designation* for the treatment of ALS by the European EMA, and the American FDA.
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Tudcabil (Tudca)
A bile salt that is found naturally occurring in the body. It has been granted orphan designation* by the European Medicines Authority (EMA) for the treatment of ALS.
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Ammonaps (sodium phenylbutyrate)
A medication used for the treatment of patients who have urea cycle disorders. Neurologists sometimes prescribe Ammonaps for off-label treatment of people suffering from ALS.
+Read more✢ Generic drugs are medicines created to be the same as an already marketed brand-name drug in dosage form, safety, strength, route of administration, quality, performance characteristics, and intended use. A generic medicine works in the same way and provides the same clinical benefit as its brand-name version.
* Orphan drugs are medicines targeting conditions which are so rare that they are unlikely to generate sufficient profit to justify research and development costs. Each regulatory agency (e.g. the FDA or EMA) has an independent process for assigning orphan drug status. Sponsors of these medicines receive incentives from the agencies to support and facilitate the development and authorisation of these therapeutics.
If you would like to know more about any of the medicines above and how you might be able to access them, you can speak to one of our qualified pharmacists.
Get in touchData from Patients *
Gender
Age at first symptom
Common symptoms
* These data have been taken from the website PatientsLikeMe. This platform was initially built for people with ALS, with the intention of connecting patients. The platform has now grown to include more than 600,000 patients who track and report on their experiences with 2,800 conditions and is one of the largest archives of patient-reported, data available today.
On PatientsLikeMe, there are a total of 12,230 patients who have amyotrophic lateral sclerosis. Not everyone has contributed to all of these statistics 4.
More information about Amyotrophic Lateral Sclerosis (ALS)
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![How effective is Radicava/Radicut (edaravone) for ALS?]()
How effective is Radicava/Radicut (edaravone) for ALS?
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Radicava/Radicut (edaravone) for ALS
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If you are a patient with ALS or have a relative with ALS, you might want to ask questions about the medicine for this disease. If you’d like to ask questions about how to get a medicine for ALS, or about our service in general, our team of qualified pharmacists and experts are ready to offer support and assist with queries. Our team speaks 17 different languages and is ready to help.
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